SLC5A5 Antibody - middle region : FITC (ARP43752_P050-FITC)
Product Specifications
Gene Name
Solute carrier family 5 (sodium iodide symporter), member 5
Gene Aliases
NIS, TDH1
Gene ID
6528
Swiss Prot
Q92911
Accession Number
NP_000444
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLC5A5
Target
The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
ERBB2IP; SLC5A5
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
SLC5A5 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
69kDa
References & Citations
Fenton, M.S., (2008) Endocrinology 149 (5), 2592-2606
Shipping Conditions
Wet Ice
Protein Length
643
NCBI Gene Symbol
SLC5A5
NCBI GB Accession Number
SLC5A5
Host or Source
Rabbit
Protein Name
Sodium/iodide cotransporter
Nucleotide Accession Number
NM_000453
Peptide Sequence
PSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRP
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