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SLC5A5 Antibody - middle region : Biotin (ARP43752_P050-Biotin)

Selected Variant

ARP43752_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Solute carrier family 5 (sodium iodide symporter), member 5

Gene Aliases

NIS, TDH1

Gene ID

6528

Swiss Prot

Q92911

Accession Number

NP_000444

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SLC5A5

Target

The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ERBB2IP; SLC5A5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SLC5A5 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Fenton, M.S., (2008) Endocrinology 149 (5), 2592-2606

Shipping Conditions

Wet Ice

Protein Length

643

NCBI Gene Symbol

SLC5A5

NCBI GB Accession Number

SLC5A5

Host or Source

Rabbit

Protein Name

Sodium/iodide cotransporter

Nucleotide Accession Number

NM_000453

Peptide Sequence

PSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRP

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