CREBBP Antibody - N-terminal region : Biotin (ARP43609_P050-Biotin)

Product Specifications

Gene Name

CREB binding protein

Gene Aliases

CBP, RSTS, KAT3A, MKHK1, RSTS1

Gene ID

1387

Swiss Prot

Q4LE28

Accession Number

NP_001073315

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CREBBP

Target

CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.

Partner Proteins

SUMO1; UBE2I; UBE2D1; TDG; RELA; CREBBP; KLF2; KLF4; WRN; PSME3; COPS2; UBC; BMI1; EID1; ATF4; DYRK1B; DYRK1A; ATF2; CREB1; CDK2; JUN; PPARG; IRF3; HNF4A; KLF1; vIRF-3; AR; vIRF-1; CNTN2; SMAD3; SMAD2; LDLR; STAT1; K8; MTDH; MEIS1; TLR2; EPAS1; MYBL1; LIG

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.