Hdac4 Antibody - C-terminal region : Biotin (ARP43602_P050-Biotin)
Selected Variant
ARP43602_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
HD4, 4932408F19Rik
Gene ID
208727
Swiss Prot
Q6NZM9
Accession Number
NP_997108
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Hdac4
Target
Hdac4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Partner Proteins
Rfxank; Mef2d; Mef2c; Mef2a; Dnajb6; Tnf; Runx2; Myocd; Ppp2ca; Gli2; Creb1; Atm; Ywhab; Ifrd1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
CHIP, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 77%; Human: 100%; Mouse: 86%; Rat: 93%; Yeast: 82%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
118kDa
Shipping Conditions
Wet Ice
Protein Length
1076
NCBI Gene Symbol
HDAC4
NCBI GB Accession Number
Hdac4
Host or Source
Rabbit
Protein Name
Histone deacetylase 4
Nucleotide Accession Number
NM_207225
Peptide Sequence
SSTVGHSLIEAQKCEKEEAETVTAMASLSVGVKPAEKRSEEEPMEEEPPL
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