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CCNB1 Antibody - C-terminal region : Biotin (ARP43600_P050-Biotin)

Product Specifications

Gene Name

Cyclin B1

Gene Aliases

CCNB

Gene ID

891

Swiss Prot

P14635

Accession Number

NP_114172

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CCNB1

Target

CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CDC27; CDC20; CDH1; ANAPC11; FZR1; ANAPC4; SIRT1; BTRC; CDC16; UBC; CDKN1A; VCP; Samhd1; CKS2; CKS1B; RHOBTB3; CDK1; CDK5; CDK2; SQSTM1; PTMA; TP73; TP53BP1; POLA1; RB1; CDK7; HIST1H1B; CDC6; CCNB1IP1; MFN1; MARCH5; PRC1; HIST1H1A; SDHAF2; NDC80; CDT1; RP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CCNB1 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 95%; Dog: 95%; Guinea Pig: 85%; Horse: 90%; Human: 100%; Pig: 95%; Rabbit: 95%; Rat: 80%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Smith, E.M. (2008) EMBO J. 27 (7), 1005-1016

Shipping Conditions

Wet Ice

Protein Length

433

NCBI Gene Symbol

CCNB1

NCBI GB Accession Number

CCNB1

Host or Source

Rabbit

Protein Name

G2/mitotic-specific cyclin-B1

Nucleotide Accession Number

NM_031966

Peptide Sequence

AKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV

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