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RXRA Antibody - N-terminal region : Biotin (ARP43586_P050-Biotin)

Product Specifications

Gene Name

Retinoid X receptor, alpha

Gene Aliases

NR2B1

Gene ID

6256

Swiss Prot

P19793

Accession Number

NP_002948

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RXRA

Target

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

PPARG; VDR; NCOA1; NSD1; UBC; NR1I3; NCOA4; THRB; THRA; ALOX15B; RARA; PPARA; CHD9; PRKD2; NR0B2; STAT1; NR3C2; SMAD2; GK; JAZF1; ACVR1B; NR1I2; NCOA2; PSMC5; RAD54L2; ARID5A; PML; SUMO1; ESR2; ESR1; BHLHE40; BHLHE41; NR4A1; EP300; NCOR1; NCOA6; NCOA3; TR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RXRA is strongly supported by BioGPS gene expression data to be expressed in HepG2, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 75%; Dog: 88%; Guinea Pig: 88%; Human: 100%; Mouse: 88%; Rat: 88%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Clark, H.F., (2008) Mol. Cell. Biol. 28 (11), 3817-3829

Shipping Conditions

Wet Ice

Protein Length

462

NCBI Gene Symbol

RXRA

NCBI GB Accession Number

RXRA

Host or Source

Rabbit

Protein Name

Retinoic acid receptor RXR-alpha

Nucleotide Accession Number

NM_002957

Peptide Sequence

DTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPI

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