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SP1 Antibody - middle region : HRP (ARP43585_P050-HRP)

Selected Variant

ARP43585_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Sp1 transcription factor

Gene ID

6667

Swiss Prot

P08047

Accession Number

NP_612482

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SP1

Target

SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.

Partner Proteins

JUN; UBC; HIC1; HDAC1; SP3; TP53; CTNNB1; ARHGAP21; SENP6; C3orf17; USP39; FOXM1; ESR1; DDX5; KIF1A; PPIG; TPI1; TFAP2A; NAP1L1; HDAC2; NUP62; MYC; HIF1A; POU2F1; SMAD3; DDX3X; TBP; SP1; RBL1; Taf4; tat; ESR2; VHL; YY1; CASP7; CASP6; CASP3; HTT; BRCA1; MA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 87%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

81kDa

References & Citations

Yoshimura, M., (2008) Biochem. Biophys. Res. Commun. 369 (3), 939-942

Shipping Conditions

Wet Ice

Protein Length

785

NCBI Gene Symbol

SP1

NCBI GB Accession Number

SP1

Host or Source

Rabbit

Protein Name

Transcription factor Sp1

Nucleotide Accession Number

NM_138473

Peptide Sequence

TLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGL

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