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DECR2 Antibody - N-terminal region : Biotin (ARP43566_T100-Biotin)

Product Specifications

Gene Name

2,4-dienoyl CoA reductase 2, peroxisomal

Gene Aliases

PDCR, SDR17C1

Gene ID

26063

Swiss Prot

Q9NUI1

Accession Number

NP_065715

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DECR2

Target

DECR2 is auxiliary enzyme of beta-oxidation. It participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. It catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA and has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

Partner Proteins

PEX5; EP300; UBC; APP; NEDD4L

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

DECR2 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

De (2001) Biochim. Biophys. Acta 1533 (1), 66-72

Shipping Conditions

Wet Ice

Protein Length

292

NCBI Gene Symbol

DECR2

NCBI GB Accession Number

DECR2

Host or Source

Rabbit

Protein Name

Peroxisomal 2,4-dienoyl-CoA reductase

Nucleotide Accession Number

NM_020664

Peptide Sequence

MAQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMR

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