GCDH Antibody - C-terminal region: Biotin (ARP43559_T100-Biotin)
Product Specifications
Gene Name
Glutaryl-CoA dehydrogenase
Gene Aliases
GCD, ACAD5
Gene ID
2639
Swiss Prot
Q92947
Accession Number
NP_000150
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GCDH
Target
GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Partner Proteins
UBC; FBXO6; ADRB2; RNF32; EXOC6; ECSIT; MAST1; CDC37; PSEN2; PSEN1; NOS3; APOE; A2M; UBD; MYC; GCDH
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/mL
Homology
Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
Shipping Conditions
Wet Ice
Protein Length
438
NCBI Gene Symbol
GCDH
Protein Name
Glutaryl-CoA dehydrogenase, mitochondrial
Nucleotide Accession Number
NM_000159
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items