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PEMT Antibody - C-terminal region : FITC (ARP43558_P050-FITC)

Product Specifications

Gene Name

Phosphatidylethanolamine N-methyltransferase

Gene Aliases

PLMT, PNMT, PEAMT, PEMPT, PEMT2

Gene ID

10400

Swiss Prot

Q9BW86

Accession Number

NP_680477

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PEMT

Target

PEMT is an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene encodes PEMT protein is within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.

Partner Proteins

SPP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

References & Citations

Xu, X., (er) FASEB J. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

236

NCBI Gene Symbol

PEMT

NCBI GB Accession Number

PEMT

Host or Source

Rabbit

Protein Name

Phosphatidylethanolamine N-methyltransferase

Nucleotide Accession Number

NM_148172

Peptide Sequence

GWAIMHASPTGLLLTVLVALTYIVALLYEEPFTAEIYRQKASGSHKRS

Frequently Asked Questions

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