PAM Antibody - C-terminal region : FITC (ARP43549_P050-FITC)
Selected Variant
ARP43549_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Peptidylglycine alpha-amidating monooxygenase
Gene Aliases
PAL, PHM
Gene ID
5066
Swiss Prot
P19021
Accession Number
NP_000910.2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human PAM
Target
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 87%; Rat: 93%; Zebrafish: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
Shipping Conditions
Wet Ice
Protein Length
335
NCBI Gene Symbol
PAM
NCBI GB Accession Number
PAM
Host or Source
Rabbit
Protein Name
Peptidyl-glycine alpha-amidating monooxygenase
Nucleotide Accession Number
NM_000919.3
Peptide Sequence
GLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEEYSAPLPALA
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