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M6PR Antibody - N-terminal region : Biotin (ARP43519_T100-Biotin)

Selected Variant

ARP43519_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Mannose-6-phosphate receptor (cation dependent)

Gene Aliases

SMPR, MPR46, CD-MPR, MPR 46, MPR-46, CD-M6PR

Gene ID

4074

Swiss Prot

P20645

Accession Number

NP_002346

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human M6PR

Target

M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

Partner Proteins

FBXO6; ATP4A; SNRPGP15; HPDL; RPS28; RPL37A; RPL6; RANBP2; NDUFS4; NDUFB4; ACP2; ACOX1; GGA3; GGA1; JUN; UBC; GGA2; PLIN3; REN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Chen, J.J., (2004) Cell 119 (7), 915-926

Shipping Conditions

Wet Ice

Protein Length

277

NCBI Gene Symbol

M6PR

NCBI GB Accession Number

M6PR

Host or Source

Rabbit

Protein Name

Cation-dependent mannose-6-phosphate receptor

Nucleotide Accession Number

NM_002355

Peptide Sequence

RLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKE

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