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TRIM54 Antibody - N-terminal region : HRP (ARP43486_P050-HRP)

Selected Variant

ARP43486_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Tripartite motif containing 54

Gene Aliases

MURF, RNF30, muRF3, MURF-3

Gene ID

57159

Swiss Prot

Q9BYV2

Accession Number

NP_115935

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM54

Target

TRIM54 contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Partner Proteins

KRT6A; CCDC146; TSHZ3; TRIM54; EXOSC5; LIN37; NGLY1; RCOR3; TBC1D22B; RBM41; CCDC87; WDYHV1; C1orf109; ING3; DCUN1D1; MBD3; SPG21; VPS28; CHCHD2; RABGEF1; CYTH4; INPP5J; OSTF1; CCDC28A; ARFIP2; KDM1A; SNF8; MID2; FARS2; DNAL4; THOC1; EPM2AIP1; ELMO1; UTP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Hillier, L.W., (2005) Nature 434 (7034), 724-731

Shipping Conditions

Wet Ice

Protein Length

400

NCBI Gene Symbol

TRIM54

NCBI GB Accession Number

TRIM54

Host or Source

Rabbit

Protein Name

Tripartite motif-containing protein 54

Nucleotide Accession Number

NM_032546

Peptide Sequence

NFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCA

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