TRIM54 Antibody - N-terminal region : Biotin (ARP43486_P050-Biotin)
Product Specifications
Gene Name
Tripartite motif containing 54
Gene Aliases
MURF, RNF30, muRF3, MURF-3
Gene ID
57159
Swiss Prot
Q9BYV2
Accession Number
NP_115935
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM54
Target
TRIM54 contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Partner Proteins
KRT6A; CCDC146; TSHZ3; TRIM54; EXOSC5; LIN37; NGLY1; RCOR3; TBC1D22B; RBM41; CCDC87; WDYHV1; C1orf109; ING3; DCUN1D1; MBD3; SPG21; VPS28; CHCHD2; RABGEF1; CYTH4; INPP5J; OSTF1; CCDC28A; ARFIP2; KDM1A; SNF8; MID2; FARS2; DNAL4; THOC1; EPM2AIP1; ELMO1; UTP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
References & Citations
Hillier, L.W., (2005) Nature 434 (7034), 724-731
Shipping Conditions
Wet Ice
Protein Length
400
NCBI Gene Symbol
TRIM54
NCBI GB Accession Number
TRIM54
Host or Source
Rabbit
Protein Name
Tripartite motif-containing protein 54
Nucleotide Accession Number
NM_032546
Peptide Sequence
NFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCA
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