UBE2C Antibody - middle region: HRP (ARP43474_P050-HRP)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression.

ANAPC11; FZR1; KLHL2; UBE2C; PCGF3; UBC; MAPK7; UBA1; BAG3; TNNC1; CXCR1; Rag1; TTC9C; UNK; ZFYVE19; UBQLN4; UBXN1; UBQLN1; UBXN7; TTLL12; SEC24A; AHCYL1; SSSCA1; YAP1; UBE4B; USP34; ZRANB2; ATP6V1F; USP9X; UBE2V1; UBE2B; TYMS; TRIP6; PSMC6; PSMA5; PPM1G

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.