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LNX1 Antibody - C-terminal region : FITC (ARP43367_T100-FITC)

Selected Variant

ARP43367_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Ligand of numb-protein X 1, E3 ubiquitin protein ligase

Gene Aliases

LNX, MPDZ, PDZRN2

Gene ID

84708

Swiss Prot

Q8TBB1-2

Accession Number

NP_116011

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human LNX1

Target

LNX1 is a membrane-bound protein that is involved in signal transduction and protein interactions. LNX1 is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis.This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

Partner Proteins

GRB2; TRIP13; ZCCHC10; ROPN1; NECAB2; PRR13; ZNF581; APIP; MEMO1; ZNF593; OSGIN1; NME7; OSBP2; DNPEP; ISCU; MTUS2; RUVBL2; NEK6; RFPL3; AIDA; GDI1; ROBO3; PBLD; LSM2; HOMEZ; TRIM54; AGTRAP; LGALS14; TRIM39; NXT2; ZFP64; POMGNT1; GOLPH3L; TRMT12; FAM118A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Weiss, A., (2007) FEBS Lett. 581 (26), 5131-5136

Shipping Conditions

Wet Ice

Protein Length

632

NCBI Gene Symbol

LNX1

NCBI GB Accession Number

LNX1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase LNX

Nucleotide Accession Number

NM_032622

Peptide Sequence

SHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVA

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