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TRIM63 Antibody - C-terminal region : HRP (ARP43364_P050-HRP)

Selected Variant

ARP43364_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Tripartite motif containing 63, E3 ubiquitin protein ligase

Gene Aliases

IRF, SMRZ, MURF1, MURF2, RNF28

Gene ID

84676

Swiss Prot

Q969Q1

Accession Number

NP_115977

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRIM63

Target

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Partner Proteins

UBE2D3; UBE2D1; UBC; TRIM63; USP37; ANKIB1; EPN1; ATXN3; EPS15; DCAF6; LMCD1; ANKRD1; NOMO1; GMEB1; NEBL; PIAS3; MRPL19; MYOT; PIAS2; SQSTM1; TCAP; PIAS1; UXT; UQCRC1; TTN; TNNI3; TNNI2; TNNI1; GFM1; TRIM55; MRPL41; MYOZ1; NEB; NDUFA1; MYBPC3; MYBPC1; EIF

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

353

NCBI Gene Symbol

TRIM63

NCBI GB Accession Number

TRIM63

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase TRIM63

Nucleotide Accession Number

NM_032588

Peptide Sequence

TIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQ

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