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SYVN1 Antibody - C-terminal region : FITC (ARP43361_P050-FITC)

Product Specifications

Gene Name

Synovial apoptosis inhibitor 1, synoviolin

Gene Aliases

DER3, HRD1

Gene ID

84447

Swiss Prot

Q86TM6

Accession Number

NP_115807

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SYVN1

Target

SYVN1 is a protein involved in endoplasmic reticulum (ER) -associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

Partner Proteins

Rer1; OS9; SEL1L; STXBP5L; UBC; SYVN1; DERL2; HEY2; HEY1; USP19; Ube2g2; MARCH6; VCP; YOD1; ATXN3; DERL1; HERPUD1; TP53; BSG; ASGR1; GPR37; UBE2D3; UBE2D2; USP7; ATN1; APOB; ERLEC1; UBXN8; SHH; ERN1; ASGR2; SARAF; FAM8A1; TYR; AUP1; ERLIN2; SGK1; ATP6AP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

References & Citations

Cattaneo, M., (2008) J. Cell. Physiol. 215 (3), 794-802

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SYVN1 (ARP43361_P050-FITC) antibody

Protein Length

616

NCBI Gene Symbol

SYVN1

NCBI GB Accession Number

SYVN1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase synoviolin

Nucleotide Accession Number

NM_032431

Peptide Sequence

ARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVV

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