SYVN1 Antibody - C-terminal region : Biotin (ARP43361_P050-Biotin)
Product Specifications
Gene Name
Synovial apoptosis inhibitor 1, synoviolin
Gene Aliases
DER3, HRD1
Gene ID
84447
Swiss Prot
Q86TM6
Accession Number
NP_115807
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human SYVN1
Target
SYVN1 is a protein involved in endoplasmic reticulum (ER) -associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER) -associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.
Partner Proteins
Rer1; OS9; SEL1L; STXBP5L; UBC; SYVN1; DERL2; HEY2; HEY1; USP19; Ube2g2; MARCH6; VCP; YOD1; ATXN3; DERL1; HERPUD1; TP53; BSG; ASGR1; GPR37; UBE2D3; UBE2D2; USP7; ATN1; APOB; ERLEC1; UBXN8; SHH; ERN1; ASGR2; SARAF; FAM8A1; TYR; AUP1; ERLIN2; SGK1; ATP6AP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
67kDa
References & Citations
Cattaneo, M., (2008) J. Cell. Physiol. 215 (3), 794-802
Shipping Conditions
Wet Ice
Protein Length
616
NCBI Gene Symbol
SYVN1
NCBI GB Accession Number
SYVN1
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase synoviolin
Nucleotide Accession Number
NM_032431
Peptide Sequence
ARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVV
Frequently Asked Questions
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