ITCH Antibody - N-terminal region: Biotin (ARP43347_P050-Biotin)
Product Specifications
Gene Name
Itchy E3 ubiquitin protein ligase
Gene Aliases
AIF4, AIP4, ADMFD, NAPP1
Gene ID
83737
Swiss Prot
A9Z1X3
Accession Number
NP_113671
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ITCH
Target
Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like prot
Partner Proteins
GSN; UBE2L3; UBC; ITCH; WWOX; GGA3; UBE2D2; PTCH1; ATXN3; HTT; EGFR; SMAD6; DTX3L; CXCR4; LATS1; POLR2A; HNRNPL; EWSR1; RPAP2; CPSF7; RPAP3; UBAP2; PABPC1; DAZAP1; WBP2; SMARCE1; SMARCC2; SMARCC1; POLR2E; POLR2C; SPG20; HNRNPUL1; UBAP2L; URI1; ARID1A; SF1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 92%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rabbit: 93%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
99kDa
Shipping Conditions
Wet Ice
Protein Length
862
NCBI Gene Symbol
ITCH
Nucleotide Accession Number
NM_031483
Curated Selection
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