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MARCH7 Antibody - middle region : Biotin (ARP43307_P050-Biotin)

Product Specifications

Gene Name

Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase

Gene Aliases

AXO, AXOT, MARCH7, RNF177, MARCH-VII

Gene ID

64844

Swiss Prot

Q9H992

Accession Number

NP_073737

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MARCH7

Target

MARCH7 is an E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Partner Proteins

MARCH7; UBE2M; UBE2N; UBE2E1; UBE2D3; UBE2D2; UBE2D1; PPP3CB; PPP3CA; MAPT; UBC; UBE2K; USP7; TRIM65; RNF111; USP9X; VAV2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

78kDa

References & Citations

Muthukumarana, P.A., Int. Immunopharmacol. 6 (13-14), 1993-2001 (2006)

Shipping Conditions

Wet Ice

Protein Length

704

NCBI Gene Symbol

44992

NCBI GB Accession Number

44992

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase MARCH7

Nucleotide Accession Number

NM_022826

Peptide Sequence

SSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVP

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