DTX2 Antibody - C-terminal region : FITC (ARP43285_P050-FITC)
Selected Variant
ARP43285_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Deltex homolog 2 (Drosophila)
Gene Aliases
RNF58
Gene ID
113878
Swiss Prot
Q6XM87
Accession Number
NP_001096066
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DTX2
Target
DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Partner Proteins
KRTAP26-1; RFX6; KLC3; GLYCTK; DTX2; RIMBP3; C1orf94; NCALD; PLEKHF2; TRIM54; EIF4ENIF1; ALKBH4; UBE2D4; HPCAL4; SPG21; SEC22A; SPAG8; STX12; NCS1; FAM168A; RBPMS; SEC23B; ABHD16A; VSNL1; SUMO1; UBE2D3; UBE2D1; UBC; TRIP6; QARS; HDC; GOLGA2; FHL2; ARNT2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
Shipping Conditions
Wet Ice
Protein Length
575
NCBI Gene Symbol
DTX2
NCBI GB Accession Number
DTX2
Host or Source
Rabbit
Protein Name
Probable E3 ubiquitin-protein ligase DTX2
Nucleotide Accession Number
NM_001102596
Peptide Sequence
EDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLE
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