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HACE1 Antibody - middle region : Biotin (ARP43277_P050-Biotin)

Product Specifications

Gene Name

HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

Gene Aliases

SPPRS

Gene ID

57531

Swiss Prot

Q8IYU2

Accession Number

NP_065822

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HACE1

Target

HACE1 contains 6 ANK repeats and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. HACE1 is an E3 ubiquitin-protein ligase that may function in cellular proteins degradation.

Partner Proteins

UBE2L3; UBC; OPTN; Unc45b; Flna; Actn1; Cald1; Lima1; Actn4; Tpm3; Tmod3; Coro1c; Vim; Vcl; Tubb5; Tubb4a; Tpm2; Tpm1; Tcp1; Plec; Sqstm1; Npm1; Myh9; Marcks; Hspa9; Hsp90ab1; Hspd1; Hspa8; Fhl1; Csrp1; Cnn2; Cct8; Serpinh1; Capzb; Capza2; Capza1; Actg1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

102kDa

References & Citations

Zhang, L., (2007) Nat. Med. 13 (9), 1060-1069

Shipping Conditions

Wet Ice

Protein Length

909

NCBI Gene Symbol

HACE1

NCBI GB Accession Number

HACE1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase HACE1

Nucleotide Accession Number

NM_020771

Peptide Sequence

DVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRV

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