IRF1 Antibody - middle region : HRP (ARP43247_P050-HRP)
Selected Variant
ARP43247_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Male-specific lethal 2 homolog (Drosophila)
Gene Aliases
MAR, IRF-1
Gene ID
3659
Swiss Prot
P10914
Accession Number
NP_002189
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human IRF1
Target
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Partner Proteins
SUMO2; SUMO3; IRF2; KAT2B; EP300; PRDM1; UBC; BIRC3; MDM2; HIST1H3A; CBL; HSP90AA1; HSPA1A; Tbk1; STUB1; SPI1; QARS; IRF8; CDKN1B; TRIM28; SET; SP2; IRF9; YBX1; NPM1; TRMT2A; HCFC1; SEC63; KEAP1; TRAF3; CREBBP; tat; SMARCA4; STAT1; HMGA1; RELA; NFKB1; KAT
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
Shipping Conditions
Wet Ice
Protein Length
325
NCBI Gene Symbol
IRF1
NCBI GB Accession Number
IRF1
Host or Source
Rabbit
Protein Name
Male-specific lethal 2 homolog
Nucleotide Accession Number
NM_002198
Peptide Sequence
NFQVSPMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNE
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