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HERC6 Antibody - N-terminal region : HRP (ARP43237_P050-HRP)

Product Specifications

Gene Name

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

Gene Aliases

FLJ20637

Gene ID

55008

Swiss Prot

Q8IVU3

Accession Number

NP_060382

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HERC6

Target

HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) -like domain (RLD) . The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]) .

Partner Proteins

FUS; UBC; HSP90AA1; UBQLN2; HERC4; HERC3; NME2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HERC6 is supported by BioGPS gene expression data to be expressed in HEK293

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

115kDa

Shipping Conditions

Wet Ice

Protein Length

1022

NCBI Gene Symbol

HERC6

NCBI GB Accession Number

HERC6

Host or Source

Rabbit

Protein Name

Probable E3 ubiquitin-protein ligase HERC6

Nucleotide Accession Number

NM_017912

Peptide Sequence

LSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH

Frequently Asked Questions

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