Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

UBR2 Antibody - C-terminal region : HRP (ARP43188_P050-HRP)

Selected Variant

ARP43188_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Ubiquitin protein ligase E3 component n-recognin 2

Gene Aliases

C6orf133, bA49A4.1, dJ242G1.1, dJ392M17.3

Gene ID

23304

Swiss Prot

Q8IWV8

Accession Number

NP_056070

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human UBR2

Target

Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]) .[supplied by OMIM].

Partner Proteins

Vif; UBC; UBE2H; RECQL4; HIST1H2BG; HIST2H2AC; TIRAP; UBE2Z; UBXN1; UBXN7; FAF2; FAF1; UBE2B; MYC; HNRNPA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that UBR2 is expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

200kDa

References & Citations

Zenker, M., (2005) Nat. Genet. 37 (12), 1345-1350

Shipping Conditions

Wet Ice

Protein Length

1755

NCBI Gene Symbol

UBR2

NCBI GB Accession Number

UBR2

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase UBR2

Nucleotide Accession Number

NM_015255

Peptide Sequence

QGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHAQEANQTLVGIDWQHL

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Vimentin (VM452), CF640R conjugate, 0.1mg/mL
BNC400452-100 1x 100 µL

Vimentin (VM452), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-FKBP135/FKBP15 Antibody Picoband®, Dylight594 Conjugate
A10447-1-Dylight594 100 µg

Anti-FKBP135/FKBP15 Antibody Picoband®, Dylight594 Conjugate

Sign In for Pricing
View Details
Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF640R conjugate, 0.1mg/mL
BNC401832-500 1x 500 µL

Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD6 (C6/372), 0.2mg/mL
BNUB0372-100 1x 100 µL

CD6 (C6/372), 0.2mg/mL

Sign In for Pricing
View Details
Anti-AGR2/Ag 2 Rabbit Monoclonal Antibody
M02922 100 µL/Vial

Anti-AGR2/Ag 2 Rabbit Monoclonal Antibody

Sign In for Pricing
View Details
KMT6/EZH2 Recombinant Rabbit Monoclonal Antibody [PSH04-14]
HA722095 100 µL

KMT6/EZH2 Recombinant Rabbit Monoclonal Antibody [PSH04-14]

Sign In for Pricing
View Details