PDZRN3 Antibody - N-terminal region : FITC (ARP43177_P050-FITC)
Selected Variant
ARP43177_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
PDZ domain containing ring finger 3
Gene Aliases
LNX3, SEMCAP3, SEMACAP3
Gene ID
23024
Swiss Prot
Q9UPQ7-3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDZRN3
Target
PDZRN3 is a E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Partner Proteins
Dlg4; LNX2; LNX1; UBE2D2; MUSK; PDZRN3; BMPR2; EFNB2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 93%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
80kDa
Shipping Conditions
Wet Ice
Protein Length
729
NCBI Gene Symbol
PDZRN3
NCBI GB Accession Number
PDZRN3
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase PDZRN3
Peptide Sequence
ELDRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCP
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