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FBXO21 Antibody - N-terminal region : Biotin (ARP43175_P050-Biotin)

Product Specifications

Gene Name

F-box protein 21

Gene Aliases

FBX21

Gene ID

23014

Swiss Prot

O94952

Accession Number

NP_055817

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO21

Target

FBXO21 contains 1 F-box domain. It is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.

Partner Proteins

TP53; CDKN1A; SUMO1; SMURF1; NEDD8; UBC; COPS5; COPS6; CUL1; ELAVL1; CNTNAP4; TERF2; TERF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

FBXO21 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71kDa

References & Citations

Nakayama, M., (2002) Genome Res. 12 (11), 1773-1784

Shipping Conditions

Wet Ice

Protein Length

621

NCBI Gene Symbol

FBXO21

NCBI GB Accession Number

FBXO21

Host or Source

Rabbit

Protein Name

F-box only protein 21

Nucleotide Accession Number

NM_015002

Peptide Sequence

KEQFRVRWPSLMKHYSPTDYVNWLEEYKVRQKAGLEARKIVASFSKRFFS

Frequently Asked Questions

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