UBE3C Antibody - N-terminal region : FITC (ARP43163_P050-FITC)
Selected Variant
ARP43163_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Ubiquitin protein ligase E3C
Gene Aliases
HECTH2
Gene ID
9690
Swiss Prot
Q15386-3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBE3C
Target
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. UBE3C can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. It has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Partner Proteins
UBC; GOLGA2; PSMD14; SHFM1; UBE2D1; PSMD2; PSMC5; PANK4; EEF2K; WDR92; TLK1; MTA2; ECT2; CPEB4; THOC7; RBM15; THOC2; WDR74; KDM1A; USP13; UTRN; PHKA2; APP; UBE2L3; UBE3C; PSMA2; ELAVL1; RAD21; MYC; CAND2; PSMD6
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
44kDa
Shipping Conditions
Wet Ice
Protein Length
404
NCBI Gene Symbol
UBE3C
NCBI GB Accession Number
UBE3C
Host or Source
Rabbit
Protein Name
Ubiquitin-protein ligase E3C
Peptide Sequence
MFSFEGDFKTRPKVSLGGASRKYSIQRSAFDRCATLSQSGGAFPIANGPN
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