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HERC3 Antibody : FITC (ARP43160_P050-FITC)

Product Specifications

Gene Name

HECT and RLD domain containing E3 ubiquitin protein ligase 3

Gene ID

8916

Swiss Prot

Q15034

Accession Number

NP_055421

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence IPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLL

Target

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

CCL22; CD33; UBE2L3; UBE2D1; UBC; TK1; UBA52; HERC6; UBQLN1; UBQLN2; NME2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

117 kDa

Shipping Conditions

Wet Ice

Protein Length

1050

NCBI Gene Symbol

HERC3

NCBI GB Accession Number

HERC3

Host or Source

Rabbit

Protein Name

Probable E3 ubiquitin-protein ligase HERC3

Nucleotide Accession Number

NM_014606

Peptide Sequence

IPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLL

Frequently Asked Questions

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