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FBXO25 Antibody - N-terminal region : Biotin (ARP43117_P050-Biotin)

Product Specifications

Gene Name

F-box protein 25

Gene Aliases

FBX25

Gene ID

26260

Swiss Prot

Q8TCJ0

Accession Number

NP_036305

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO25

Target

FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

SYTL2; ING3; TMA7; HP1BP3; ADRBK1; PRRG1; PRKG2; PRKCA; PPP1R8; PPID; PDGFRA; PCK1; ODF2; KRT8; KDR; IRS1; DNAJB2; HIP1; GTF2B; FKBP3; ELK1; EGFR; DCX; EID3; PRR15; APLF; TCEANC; WDSUB1; TRUB1; TCEAL2; TCP10L; ANKRD13A; C7orf50; RHBDD1; NSRP1; RABEP2; C11

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Hagens, O., (2006) Biochim. Biophys. Acta 1760 (1), 110-118

Shipping Conditions

Wet Ice

Protein Length

291

NCBI Gene Symbol

FBXO25

NCBI GB Accession Number

FBXO25

Host or Source

Rabbit

Protein Name

F-box only protein 25

Nucleotide Accession Number

NM_012173

Peptide Sequence

LGEAFNRLDFSSAIQDIRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNIL

Frequently Asked Questions

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