WWP2 Antibody - C-terminal region : Biotin (ARP43089_P050-Biotin)

Product Specifications

Gene Name

WW domain containing E3 ubiquitin protein ligase 2

Gene Aliases

AIP2, WWp2-like

Gene ID

11060

Swiss Prot

O00308

Accession Number

NP_955456

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human WWP2

Target

WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

LGALS9B; ANKRD44; FBXL18; VPS37C; PABPC1; RUSC1; HNRNPUL1; WWP2; PAIP1; TRAF4; FAM189A2; PDLIM7; EIF3A; WIPF1; UBE2L3; UBC; SNRPC; PTCH1; SMAD6; SMAD3; EZH2; PTEN; UBE2D3; FBXL15; RNF11; ARRDC1; ARRDC4; ARRDC3; VPS11; UBE2G1; UBE2J2; UBE2E3; UBE2E1; UBE2D

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

WWP2 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.