NEDD4 Antibody - middle region : Biotin (ARP43067_P050-Biotin)

Product Specifications

Gene Name

Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase

Gene Aliases

RPF1, NEDD4-1

Gene ID

4734

Swiss Prot

B4E2R7

Accession Number

NP_006145

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NEDD4

Target

NEDD4 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4 is involved in the budding of many viruses.

Partner Proteins

RPO21; UBI4; UBC8; RNF7; SRC; POLR2A; NEDD4; CUL5; UBE2L3; UBE2D3; UBE2D1; UBC; FGFR1; SPT23; PTCH1; SMO; YOD1; TNK2; SNCA; GUCD1; FBXL18; ERBB3; CSNK1D; CCNH; RBX1; BTRC; CUL1; SKP1; PTEN; ARRDC3; MDM2; RAPGEF2; AMOTL1; POLR2M; RPAP2; EPRS; DIAPH1; DDX3X

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.