HIP2 Antibody - N-terminal region: FITC (ARP43048_T100-FITC)
Product Specifications
Gene Name
Ubiquitin-conjugating enzyme E2K
Gene Aliases
LIG, HIP2, HYPG, UBC1, E2-25K
Gene ID
3093
Swiss Prot
P61086
Accession Number
NP_005330
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HIP2
Target
HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
Partner Proteins
DDI1; DTX3; MIPOL1; TRIM39; ANAPC11; RNF138; SIAH1; RNF5; REL; FZR1; UBC; UBA1; MARCH7; AMFR; TP53; MDM2; BAG3; PRRG4; IQCB1; HTT; CDC6; WDR1; TYMS; TXN; TXNDC17; WDR61; ITCH; NEDD4L; WWP2; NXF1; NUB1; PIAS4; CASP12; SUMO1; SUMO2; DIABLO; UBE2I; CCNB1; BR
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
22kDa
Shipping Conditions
Wet Ice
Protein Length
200
NCBI Gene Symbol
UBE2K
Protein Name
Ubiquitin-conjugating enzyme E2 K
Nucleotide Accession Number
NM_005339
Curated Selection
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