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UBE4A Antibody - middle region : HRP (ARP43044_P050-HRP)

Product Specifications

Gene Name

Ubiquitination factor E4A

Gene Aliases

E4, UFD2, UBOX2

Gene ID

9354

Swiss Prot

B0YJB6

Accession Number

NP_004779

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UBE4A

Target

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4A is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.

Partner Proteins

UBC; SLA; EPHA2; CBX7; UBE2D3; ELAVL1; MAVS; PTTG1; GZMB; CASP6; UBE2D4; UBE2D2; UBE2D1; VCP; PTP4A3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

UBE4A is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

123kDa

References & Citations

Sakiyama, T., (2008) Inflamm. Bowel Dis. 14 (3), 310-317

Shipping Conditions

Wet Ice

Protein Length

1073

NCBI Gene Symbol

UBE4A

NCBI GB Accession Number

UBE4A

Host or Source

Rabbit

Protein Name

Ubiquitin conjugation factor E4 A

Nucleotide Accession Number

NM_004788

Peptide Sequence

QYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILRYMWGTDTYR

Frequently Asked Questions

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