UBE2M Antibody - N-terminal region : Biotin (ARP43030_P050-Biotin)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.

DCUN1D1; DCUN1D4; RBX1; UBC; MARCH7; UBE2M; CUL1; DCUN1D3; SMURF1; CAND1; DCUN1D2; NEDD8; DCUN1D5; LMNA; VCAM1; ITGA4; FN1; VCP; UBE2D2; TYMS; TST; VAMP2; PARK2; PINK1; UBE2T; SEC22B; SLC9A3R2; APP; CUL3; CUL4A; TP53; UBD; COPS6; UBA3; NAE1; CUL2; Nedd4

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.