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FKBP6 Antibody - middle region : FITC (ARP43027_T100-FITC)

Selected Variant

ARP43027_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

FK506 binding protein 6, 36kDa

Gene Aliases

FKBP36

Gene ID

8468

Swiss Prot

O75344

Accession Number

NP_003593

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human FKBP6

Target

FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Partner Proteins

LZTS2; CDK5RAP3; SUMO1P1; CCDC36; CDC37; USP19; PTGES3; VBP1; PFDN2; OSBP; HSP90AB1; HSP90AA1; TINF2; ACD; NME7; CCNK; GAPDH

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Ye, X.Q., (2005) Int. J. Mol. Med. 16 (5), 851-856

Shipping Conditions

Wet Ice

Protein Length

467

NCBI Gene Symbol

FKBP6

NCBI GB Accession Number

FKBP6

Host or Source

Rabbit

Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP6

Nucleotide Accession Number

NM_006147

Peptide Sequence

FCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLL

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