UBE2L3 Antibody - C-terminal region : Biotin (ARP43026_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin-conjugating enzyme E2L 3

Gene Aliases

E2-F1, L-UBC, UBCH7, UbcM4

Gene ID

7332

Swiss Prot

P68036

Accession Number

NP_003338

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human UBE2L3

Target

UBE2L3 (ubiquitin-conjugating enzyme E2L 3) Antibody The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

UBC; TRAF6; NEDD4; ITCH; MUL1; SMURF2; SMURF1; WWP2; WWP1; ARIH2; RNF144A; UBA1; PARK2; RNF144B; HACE1; ARIH1; UBE3A; UBE2L3; UBA6; UBR5; CACNA1B; MAP1LC3B; BAG3; HSPA4; AICDA; CCNB1IP1; FN1; RBX1; LIG4; ZPR1; USP9X; SF1; VDAC2; UCHL3; UBE2V2; UBE2D2; UBE

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that UBE2L3 is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.