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UBE2I Antibody - N-terminal region : Biotin (ARP43021_T100-Biotin)

Product Specifications

Gene Name

Ubiquitin-conjugating enzyme E2I

Gene Aliases

P18, UBC9, C358B7.1

Gene ID

7329

Swiss Prot

P63279

Accession Number

NP_003336

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2I

Target

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Partner Proteins

TRIM21; SP100; SUMO2; RANGAP1; PTEN; LMO2; PIAS2; TRIM23; PARP1; PIAS4; UBXN1; USP25; SETBP1; SIRT1; PUF60; HMGA1; GOLGA2; FHL3; ELK1; DES; DAXX; CREBBP; CLK2; RCBTB2; CEBPD; CBS; CAPN2; PPARGC1A; RFPL3; TRIM38; IKZF1; RNF40; XBP1; KRT19; HNRNPC; ZBTB8A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

There is BioGPS gene expression data showing that UBE2I is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Zhu, S., (2006) Exp. Cell Res. 312 (7), 1042-1049

Shipping Conditions

Wet Ice

Protein Length

158

NCBI Gene Symbol

UBE2I

NCBI GB Accession Number

UBE2I

Host or Source

Rabbit

Protein Name

SUMO-conjugating enzyme UBC9

Nucleotide Accession Number

NM_003345

Peptide Sequence

MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKG

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