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PEX10 Antibody - C-terminal region : Biotin (ARP42997_P050-Biotin)

Product Specifications

Gene Name

Peroxisomal biogenesis factor 10

Gene Aliases

NALD, PBD6A, PBD6B, RNF69

Gene ID

5192

Swiss Prot

O60683

Accession Number

NP_002608

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PEX10

Target

PEX10 is a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in PEX10 gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome.This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.

Partner Proteins

HNRNPD; PEX5; PEX14; LIG4; PCGF6; CGRRF1; MKRN3; PEX19; PEX12; PEX10; UBC; UBE2I; PEX2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PEX10 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

References & Citations

Gregory, S.G., (2006) Nature 441 (7091), 315-321

Shipping Conditions

Wet Ice

Protein Length

326

NCBI Gene Symbol

PEX10

NCBI GB Accession Number

PEX10

Host or Source

Rabbit

Protein Name

Peroxisome biogenesis factor 10

Nucleotide Accession Number

NM_002617

Peptide Sequence

ERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLRHYR

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