AMFR Antibody - C-terminal region: Biotin (ARP42995_T100-Biotin)
Product Specifications
Gene Name
Autocrine motility factor receptor, E3 ubiquitin protein ligase
Gene Aliases
GP78, RNF45
Gene ID
267
Swiss Prot
Q9UKV5
Accession Number
AAH56869
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR
Target
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000) .[supplied by OMIM].
Partner Proteins
VCP; UBE2G1; HSPA5; ERLIN2; INSIG1; HMGCR; DHFR; AMFR; UBE2D1; UBC; GPI; TRIM25; DGAT2; UBE2K; Ube2g2; NPLOC4; HERPUD1; BAG6; MAVS; YOD1; ADRA1D; DERL2; ADRB2; FAF2; SEC61B; RPN1; STT3A; STT3B; AUP1; MDC1; SNED1; DDOST; GET4; UBXN4; UBL4A; CD82; SARAF; IT
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
AMFR is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
73kDa
Shipping Conditions
Wet Ice
Protein Length
643
NCBI Gene Symbol
AMFR
Protein Name
AMFR protein EMBL AAH56869.1
Nucleotide Accession Number
NM_013446
Curated Selection
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