AMFR Antibody - C-terminal region : Biotin (ARP42995_T100-Biotin)

Product Specifications

Gene Name

Autocrine motility factor receptor, E3 ubiquitin protein ligase

Gene Aliases

GP78, RNF45

Gene ID

267

Swiss Prot

Q9UKV5

Accession Number

AAH56869

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR

Target

Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000) .[supplied by OMIM].

Partner Proteins

VCP; UBE2G1; HSPA5; ERLIN2; INSIG1; HMGCR; DHFR; AMFR; UBE2D1; UBC; GPI; TRIM25; DGAT2; UBE2K; Ube2g2; NPLOC4; HERPUD1; BAG6; MAVS; YOD1; ADRA1D; DERL2; ADRB2; FAF2; SEC61B; RPN1; STT3A; STT3B; AUP1; MDC1; SNED1; DDOST; GET4; UBXN4; UBL4A; CD82; SARAF; IT

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Sample Type

AMFR is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.