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HERC4 Antibody - middle region : FITC (ARP42991_P050-FITC)

Selected Variant

ARP42991_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

HECT and RLD domain containing E3 ubiquitin protein ligase 4

Gene Aliases

DKFZp564G092, KIAA1593

Gene ID

26091

Swiss Prot

Q5GLZ8

Accession Number

NP_001017972

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HERC4

Target

HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) -like domain (RLD) . The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.

Partner Proteins

UBC; SUMO2; H2AFV; DCTPP1; C9orf78; NT5C2; FKBP9; NUBP2; USP5; WARS; RAD23A; PCNA; HEXA; HSP90AA1; UBE2J2; UBE2E3; UBE2D2; HERC4; HERC6

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

13kDa

Shipping Conditions

Wet Ice

Protein Length

117

NCBI Gene Symbol

HERC4

NCBI GB Accession Number

HERC4

Host or Source

Rabbit

Nucleotide Accession Number

NM_001017972

Peptide Sequence

VGCGLRHTVFVLDDGTVYTCGCNDLGQLGHEKSRKKPEILKVCQISRLYR

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