MARCH2 Antibody - C-terminal region : FITC (ARP42967_P050-FITC)
Selected Variant
ARP42967_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Gene Aliases
MARCH2, RNF172, HSPC240, MARCH-II
Gene ID
51257
Swiss Prot
Q9P0N8
Accession Number
NP_057580
Host
Rabbit
Reactivity
Human, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARCH2
Target
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.
Partner Proteins
LDLRAD1; SYNE4; CCDC155; FATE1; UBE2H; UBE2D1; CDC34; GOPC; STX6; CFTR; ADRB2; ELAVL1; DLG1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 90%; Human: 100%; Rabbit: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
246
NCBI Gene Symbol
44987
NCBI GB Accession Number
MARCH2
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase MARCH2
Nucleotide Accession Number
NM_016496
Peptide Sequence
IALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPL
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