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MARCH8 Antibody - N-terminal region : FITC (ARP42958_P050-FITC)

Selected Variant

ARP42958_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

Gene Aliases

MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII

Gene ID

220972

Swiss Prot

Q5T0T0

Accession Number

NP_001002265

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH8

Target

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. M

Partner Proteins

TNFRSF10A; UBC; UBE2H; UBE2D1; TFRC; UBE2D3; IL1RAP; IL1R1; CD86

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MARCH8 is supported by BioGPS gene expression data to be expressed in PANC1

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 79%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

0

Shipping Conditions

Wet Ice

Protein Length

291

NCBI Gene Symbol

44993

NCBI GB Accession Number

44993

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase MARCH8

Nucleotide Accession Number

NM_001002265

Peptide Sequence

MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS

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