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TJP2 Antibody - middle region : Biotin (ARP42941_P050-Biotin)

Product Specifications

Gene Name

Tight junction protein 2 (zona occludens 2)

Gene Aliases

ZO2, X104, FHCA1, PFIC4, DFNA51, DUP9q21.11, C9DUPq21.11

Gene ID

9414

Swiss Prot

Q9UDY2

Accession Number

NP_004808

Host

Rabbit

Reactivity

Human, Rat, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TJP2

Target

Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1975 BC027592.1 10-1984 1976-2543 L27476.1 1855-2422 2544-3080 BC028426.1 2440-2976 3081-4167 BC027592.1 3090-4176 4168-4601 L27476.1 4051-4484 4602-4618 BC028426.1 4056-4072

Partner Proteins

SNAI2; UBC; KCMF1; PGAM5; KIAA1671; LATS2; YAP1; KIF14; LATS1; TJP1; SRPK2; SRPK1; PLOD1; CDK6; ZMYM3; THOC5; UBN1; CLDN2; SIRT7; SSTR3; YWHAZ; YWHAG; YWHAB; OCLN; SRRM2; KBTBD7; RAE1; CGN; SCRIB; CLDN1; SAFB; SH3KBP1; EPB41; CTNNA1; HGS; YWHAQ; TRAF6; SF

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TJP2 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Dog: 100%; Horse: 92%; Human: 100%; Rabbit: 93%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

134kDa

References & Citations

Bel (2008) Hum. Genet. 123 (3), 267-272

Shipping Conditions

Wet Ice

Protein Length

1190

NCBI Gene Symbol

TJP2

NCBI GB Accession Number

TJP2

Host or Source

Rabbit

Protein Name

Tight junction protein ZO-2

Nucleotide Accession Number

NM_004817

Peptide Sequence

TVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKK

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