TJP2 Antibody - middle region : Biotin (ARP42941_P050-Biotin)
Product Specifications
Gene Name
Tight junction protein 2 (zona occludens 2)
Gene Aliases
ZO2, X104, FHCA1, PFIC4, DFNA51, DUP9q21.11, C9DUPq21.11
Gene ID
9414
Swiss Prot
Q9UDY2
Accession Number
NP_004808
Host
Rabbit
Reactivity
Human, Rat, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TJP2
Target
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1975 BC027592.1 10-1984 1976-2543 L27476.1 1855-2422 2544-3080 BC028426.1 2440-2976 3081-4167 BC027592.1 3090-4176 4168-4601 L27476.1 4051-4484 4602-4618 BC028426.1 4056-4072
Partner Proteins
SNAI2; UBC; KCMF1; PGAM5; KIAA1671; LATS2; YAP1; KIF14; LATS1; TJP1; SRPK2; SRPK1; PLOD1; CDK6; ZMYM3; THOC5; UBN1; CLDN2; SIRT7; SSTR3; YWHAZ; YWHAG; YWHAB; OCLN; SRRM2; KBTBD7; RAE1; CGN; SCRIB; CLDN1; SAFB; SH3KBP1; EPB41; CTNNA1; HGS; YWHAQ; TRAF6; SF
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
TJP2 is supported by BioGPS gene expression data to be expressed in MCF7
Concentration
0.5 mg/ml
Homology
Dog: 100%; Horse: 92%; Human: 100%; Rabbit: 93%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
134kDa
References & Citations
Bel (2008) Hum. Genet. 123 (3), 267-272
Shipping Conditions
Wet Ice
Protein Length
1190
NCBI Gene Symbol
TJP2
NCBI GB Accession Number
TJP2
Host or Source
Rabbit
Protein Name
Tight junction protein ZO-2
Nucleotide Accession Number
NM_004817
Peptide Sequence
TVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKK
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