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PARD6A Antibody - N-terminal region : HRP (ARP42883_P050-HRP)

Product Specifications

Gene Name

Par-6 partitioning defective 6 homolog alpha (C. elegans)

Gene Aliases

PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha

Gene ID

50855

Swiss Prot

Q3TY70

Accession Number

NP_001032358

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A

Target

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

PRKCI; WDR83; PRKCZ; FBXO31; PARD3; UBC; TUBG1; ARHGAP17; VHL; MAP2K5; TJP1; SMURF1; TGFB1; WDR92; PARD6B; PDRG1; RPAP3; MARK4; PIH1D1; SUGT1; YWHAZ; YWHAH; LLGL1; LLGL2; MARK2; CDC42; CRB3; ECT2; PLCB1; RHOQ; PRKCH; RAC1; CDH5; PLCB3; TGFBR1; TCP10; PRKC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-PARD6A (ARP42883_P050-HRP) antibody

Protein Length

345

NCBI Gene Symbol

PARD6A

NCBI GB Accession Number

PARD6A

Host or Source

Rabbit

Protein Name

Putative uncharacterized protein EMBL BAE34693.1

Nucleotide Accession Number

NM_001037281

Peptide Sequence

MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVH

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