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PARD6A Antibody - N-terminal region : HRP (ARP42883_P050-HRP)

Selected Variant

ARP42883_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Par-6 partitioning defective 6 homolog alpha (C. elegans)

Gene Aliases

PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha

Gene ID

50855

Swiss Prot

Q3TY70

Accession Number

NP_001032358

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A

Target

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

PRKCI; WDR83; PRKCZ; FBXO31; PARD3; UBC; TUBG1; ARHGAP17; VHL; MAP2K5; TJP1; SMURF1; TGFB1; WDR92; PARD6B; PDRG1; RPAP3; MARK4; PIH1D1; SUGT1; YWHAZ; YWHAH; LLGL1; LLGL2; MARK2; CDC42; CRB3; ECT2; PLCB1; RHOQ; PRKCH; RAC1; CDH5; PLCB3; TGFBR1; TCP10; PRKC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

Shipping Conditions

Wet Ice

Protein Length

345

NCBI Gene Symbol

PARD6A

NCBI GB Accession Number

PARD6A

Host or Source

Rabbit

Protein Name

Putative uncharacterized protein EMBL BAE34693.1

Nucleotide Accession Number

NM_001037281

Peptide Sequence

MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVH

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