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PANX1 Antibody - middle region : Biotin (ARP42783_P050-Biotin)

Product Specifications

Gene Name

Pannexin 1

Gene Aliases

PX1, MRS1, OOMD7, UNQ2529

Gene ID

24145

Swiss Prot

Q96RD7

Accession Number

NP_056183

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PANX1

Target

PANX1 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Partner Proteins

GNAS; UBC; P2RX7

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

PANX1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 83%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 77%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

References & Citations

Otsuki, T., (2005) DNA Res. 12 (2), 117-126

Shipping Conditions

Wet Ice

Protein Length

426

NCBI Gene Symbol

PANX1

NCBI GB Accession Number

PANX1

Host or Source

Rabbit

Protein Name

Pannexin-1

Nucleotide Accession Number

NM_015368

Peptide Sequence

LGYYFSLSSLSDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVIN

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