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ACLY Antibody - middle region : HRP (ARP42737_P050-HRP)

Product Specifications

Gene Name

ATP citrate lyase

Gene Aliases

ACL, ATPCL, CLATP

Gene ID

47

Swiss Prot

P53396

Accession Number

NP_001087

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ACLY

Target

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety

Partner Proteins

UBC; UBR4; SIRT2; HUWE1; ISG15; KAT2B; SUMO2; SUMO3; STAU1; SUMO1; NEDD8; MDM2; ASB15; WWOX; TRIM25; MAGED2; BAG3; PPP6C; NCL; MCM6; MCM2; KPNA4; KPNA2; PRMT1; CDKN2A; SRRT; UBD; FN1; APP; SHC1; CUL3; CAND1; CUL2; SIRT7; UL27; HDAC5; TERF2; TERF1; GSK3B

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

ACLY is strongly supported by BioGPS gene expression data to be expressed in ACHN

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%; Sheep: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

121kDa

References & Citations

0

Shipping Conditions

Wet Ice

Protein Length

1101

NCBI Gene Symbol

ACLY

NCBI GB Accession Number

ACLY

Host or Source

Rabbit

Protein Name

ATP-citrate synthase

Nucleotide Accession Number

NM_001096

Peptide Sequence

LRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPA

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